SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

o

Rule 13d-1(b)

o

Rule 13d-1(c)

x

Rule 13d-1(d)

CUSIP No. 36870A 108

1

Name of Reporting Person:
Charles L. Bisgaier

2

Check the Appropriate Box if a Member of a Group:

(a)

o

(b)

o

3

SEC Use Only:

4

Citizenship or Place of Organization:
United States of America

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With:

5

Sole Voting Power:
1,387,384(1)

6

Shared Voting Power:
19,228

7

Sole Dispositive Power:
1,387,384(1)

8

Shared Dispositive Power:
19,228

9

Aggregate Amount Beneficially Owned by Each Reporting Person:
1,406,612(1)

10

Check if the Aggregate Amount in Row (9) Excludes Certain Shares:  o

11

Percent of Class Represented by Amount in Row (9):
13.2%  (See Item 4 herein)

12

Type of Reporting Person:
IN

Item 1.

(a)

Name of Issuer.
Gemphire Therapeutics Inc.

(b)

Address of Issuer’s Principal Executive Offices.
17199 N. Laurel Park Drive, Suite 401, Livonia, MI 48152

Item 2.

(a)

Name of Person Filing (the “Reporting Person”).
Charles L. Bisgaier

(b)

Address or Principal Business Office or, if none, Residence.
The address for the Reporting Person is 17199 N. Laurel Park Drive, Suite 401, Livonia, MI 48152.

(c)

Citizenship.
Mr. Bisgaier is a citizen of the United States of America.

(d)

Title of Class of Securities.
Common Stock, $0.001 par value

(e)

CUSIP No.
36870A 108

Item 3.

If this statement is filed pursuant to §§.240.13d-1(b) or 240.13d-2(b), or (c), check whether the person filing is a:

(a)

o

Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b)

o

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c)

o

Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d)

o

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).

(e)

o

An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E).

(f)

o

An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F).

(g)

o

A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G).

(h)

o

A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813).

(i)

o

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3).

(j)

o

A non-U.S. institution in accordance with §240.13d-1(b)(1)(ii)(J).

(k)

o

Group, in accordance with §240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance with

§240.13d-1(b)(1)(ii)(J), please specify the type of institution.                                                        

Item 4.

Ownership.

(c)
Number of Shares as to which the person has:

Name

(a)
Amount
Beneficially
Owned

(b)
Percent
of Class*

Sole Power to
Vote or to
Direct the
Vote

Shared
Power to
Vote or to
Direct the
Vote

Sole Power to
Dispose or to
Direct the
Disposition of

Shared Power to
Dispose or to
Direct the
Disposition of

Charles L. Bisgaier

1,305,164

(1)

12.2

%

1,305,164

(1)

0

1,305,164

(1)

0

The Charles L. Bisgaier Trust(2)

82,220

0.8

%

82,220

0

82,220

0

Bisgaier Family, LLC(3)

19,228

0.2

%

0

19,228

0

19,228

Item 5.

Ownership of Five Percent or Less of a Class.

Not applicable.

Item 6.

Ownership of More than Five Percent on Behalf of Another Person.

Not applicable.

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

Not applicable.

Item 8.

Identification and Classification of Members of the Group.

Not applicable.

Item 9.

Notice of Dissolution of Group.

Not applicable.

Item 10.

Certification.

Dated: February 7, 2018

/s/ Charles L. Bisgaier

Charles L. Bisgaier